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Diffuse involvement of the gastrointestinal tract by graft versus host disease GVHD is a common complication of allogeneic hematopoietic stem cell transplant HSCT. Gastrointestinal GVHD usually presents 3 or more weeks after HSCT and is characterized by profuse diarrhea, anorexia, nausea, vomiting, abdominal pain and gastrointestinal bleeding. The patient was treated with methylprednisolone, cyclosporin and mycophenolate mofetil, with a partial response diarrhea and abdominal pain improved , but then he developed multiple other medical complications and died after 3 months. Acute graft-versus-host disease GVHD occurs after allogeneic hematopoietic stem cell IA transplantation HSCT as a consequence of an immune reaction by the donor immune cells against host tissues. The spontaneous passage of a full-thickness colon cast has been described eight times previously, 5 — 9 including one case of a mucosal cast. In five cases the etiology was occlusion of the mesenteric artery.
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Defecation of a “colon cast” as a rare presentation of acute graft-versus-host disease

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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected n , low l , medium m and high h. Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
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